Important Measures To Prevent Cross-Contamination In Cleanroom

Clean Room CorridorAvoiding cross-contamination is an important part of cleanroom dust particle control, as it's widespread.

Cross-contamination refers to the pollution caused by the mixing of different kinds of dust particles, through personnel commuting, tool transportation, material transfer, airflow, equipment cleaning and disinfection, post-clearance, and other ways. Or due to the improper flow of humans, tools, materials, air, etc., pollutants in the low-cleanliness area enter the high-cleanliness area, eventually causing cross-contamination. So, how to prevent cross-contamination?

  • Arrange reasonable space area

Firstly, a reasonable layout must straighten out the technological process flow and avoid repeat work. The plant space should be reasonable, both conducive to operation and maintenance, and should not reserve idle area and space. Reasonable space and area are also conducive to reasonable zoning and preventing miscellaneous accidents.

It should be noted that the cleanroom is not the bigger the better. The area and space are related to the amount of air volume, determine the energy consumption of the air conditioner, and affect the investment of the project. But the space of the cleanroom cannot be too small, which may not be convenient for operation and maintenance. Therefore, the design of reasonable space area should consider the requirements of equipment operation and maintenance. The space area of the production zone and storage zone should be suitable for the scale of production, to place the equipment and materials, and easy for operation and maintenance. Generally, the height of the cleanroom is controlled at 2.60 meters, and the height of the individual higher equipment can be increased accordingly, instead of entirely increasing the height of the whole clean area. There should be an intermediate station inside the workshop, with a sufficient area to store materials, intermediate products, pending inspected products and finished products, and easy to partition, to minimize errors and cross-contamination.

  • Improve equipment grade

The materials, accuracy, airtightness and management system of equipment are all related to cross-contamination. Therefore, in addition to reasonable layout, improving the automation level of equipment and forming a linked production line to reduce operators and the frequency of personnel activities is a necessary measure to prevent cross-contamination.

The air-conditioning purification system of the cleanroom should be set up according to different cleanliness levels. Partial exhaust systems should be provided separately for clean rooms with different cleanliness levels, produce dust and harmful gases, and posts with highly toxic media and flammable and explosive gases. The exhaust outlet of the cleanroom should be equipped with an anti-backflow device. The opening and closing of the supply air, return air and exhaust air should have interlocking devices.

  •  Control the flow of person and logistics strictly

The cleanroom should be equipped with dedicated flow of person and logistics channels. Personnel should enter according to the prescribed purification procedures, and the number of persons should be strictly controlled. Items in the clean area of different cleanliness grades van been conveyed through the transfer window. The intermediate station should be located in the center to shorten the transportation distance. 


Post time: Aug-05-2021